NOVEL NANOTECHNOLOGY-ENABLED SYSTEM
FOR ENDOVASCULAR IN VIVO NEAR-INFRARED FLUORESCENCE MOLECULAR IMAGING
AND ENDOVASCULAR NEAR-INFRARED TARGETED PHOTODYNAMIC THERAPY OF
ATHEROSCLEROTIC HEART DISEASE

Large-scale EU FP7 NMP funded R&D Project March 2013 - March 2018

CosmoPHOS-nano is a multidisciplinary translational and business-oriented project aiming to develop and evaluate in both nonclinical and clinical applications a novel theranostic (diagnostic & therapeutic) nanotechnology-enabled portable combination system which will enable:

  1. Endovascular in vivo near-infrared fluorescence molecular imaging;
  2. Endovascular near-infrared targeted photodynamic therapy, and;
  3. Real-time & follow-up therapy monitoring of atherosclerotic coronary artery disease (CAD).

The CosmoPHOS System is anticipated to reduce the number of deaths and morbidity caused by CAD by up to 40%, which we forecast to result in a significant decrease in European and global healthcare costs caused by CAD, increase the income of the European healthcare industry from the CAD market, which is the global largest, and alleviate the European and Global Society.

The CosmoPHOS-nano Project is the world's largest R&D Project of Nanomedicine in Cardiology, consisting of 19 world-class Participants including 13 Universities and Research Foundations and 6 Companies. These academic and industrial partners have spent more than nine years successfully collaborating, and the CosmoPHOS-nano project marks a significant milestone in the Consortium's ongoing efforts to combat the devastating effect of CAD on European and global societies.